Gastroenterology – Clinical Research

There are over 20 active clinical research projects in the Division of Gastroenterology. Almost all the projects involve trainees, including GI fellows, medical residents, and medical students. Research is facilitated by a full-time clinical research supervisor, who is available to assist with protocol design and regulatory processes, such as IRB submission, compliance, and financial management.

Current projects include:

• IBD

  • Optimize Trial: Dashboard therapeutic drug monitoring and optimization for Infliximab treatment in patients with IBD (S. Fine)
  • Real world outcomes of novel therapy agents in patients with IBD (S. Fine)
  • Racial Disparities and ability to meet treat to Target goals in patients with IBD (S. Fine)
  • Intestinal Ultrasound and clinical outcomes data (S. Fine)
  • Understanding delays in care/treatment for patients presenting with IBD flare (S. Fine)
  • IBDqorus: a nationwide consortium of collaboration and outcomes for patients with IBD (S. Fine)

• Hepatology

  • The Role of Inpatient Palliative Care Consultation in End-Stage Liver Disease: A Systematic Review and Retrospective Study (K. Promrat)
  • Biobehavioral Pathways Underlying Alcohol Use and Health (K. Promrat)

• Endoscopy

  • Food impactions and real world experience study understanding of safety, timing, sedation mode and outcomes (S. Fine)
  • Utility and outcomes of inpatient capsule endoscopy (M. Min)
  • Spray Cryotherapy Patient Registry (F. Habr)
  • Clinical psychiatric characteristics of patients undergoing moderate sedation and anesthesia assisted deep sedation for gastrointestinal procedures (H. Rich)
  • Human-Assisted Deep Learning for Capsule Endoscopy (H. Rich)

• Other

  • Outcome of H. pylori eradication therapy tailored using next generation sequencing for antibiotic susceptibility (S. Moss)
  • Development of a national H. pylori clinical registry (S. Moss)
  • GI toxicities related to immune checkpoint inhibitors (M. Min)
  • Produce prescription program to improve dietary quality in populations with obesity (B. Perler)
  • Cooking intervention in collaboration with Johnson and Wales University to improve dietary quality and healthy eating behaviors in populations with obesity (B. Perler)
  • Body composition testing with dietary biomarkers to assess disease phenotypes among patients with various GI diseases and disorders (B. Perler)
  • Composting program at Rhode Island Hospital to reduce hospital based food waste and carbon emissions (B. Perler)